Symposium on Ion channels and Channelopathies - IPMC

Massimo Mantegazza

Symposium on Ion Channels and Channelopathies
IPMC-UCA
660 Route des Lucioles, 06560 Valbonne-Sophia Antipolis, France
20 November 2018
Sponsors:
Université Côte d'Azur (UCA) - Academie 4 
http://univ-cotedazur.fr/fr/idex/academies/living-systems-complexity-and-diversity
 
UCA interdisciplinary virtual center C@UCA
http://univ-cotedazur.fr/en/idex/projet-structurant/cauca
 
LabEx Ion Channel Science &amp; Therapeutics (ICST)
http://www.labex-icst.fr/fr
 
Nanion 
https://www.nanion.de/en/
 
Multichannel Systems
https://www.multichannelsystems.com
 
9:00 Reception
 
9:20 Introduction Massimo Mantegazza (IPMC)
 
9:30 William Catterall (University of Washington, Seattle, USA) Sodium channelopathies in epileptic encephalopathies.
 
10:10 Holger Lerche (Tubingen, Germany) Mutations and variants of ion channels in monogenic and polygenic epilepsies.
 
10:40 Coffee Break
 
11:00 Massimo Mantegazza (IPMC) Differential mechanisms of Epilepsy and Migraine Caused by mutations of sodium channels.
 
11:20 Martin Krupa (UNS-UCA, Nice, France) Modeling/mathematical analysis of pathological mechanisms of sodium channels’ migraine mutations.
 
11:40 Pietro Baldelli (IIT &amp; Univ. Genoa, Italy) Synaptic-axonal crosstalk: PRRT2-Nav pathologies.
 
12:10 Ana Rita Pereira (IPMC) A two-hit story: seizures and genetic mutation interaction sets phenotype severity in SCN1A/NaV1.1 epilepsies. 
 
12:25 General discussion
 
12:35 Lunch (Nanion &amp; Multichannel Systems' Booths;13:30 Live demo from Nanion) 
 
14:00 William Catterall (University of Washington, Seattle, USA) Defects of protein structure in channelopathies.
 
14:40 Michael Pusch (CNR, Genoa, Italy) Regulation of volume-sensitive anion LRRC8 channels by oxidation.
 
15:10 Eric Lingueglia (IPMC) ASIC channels in pain diseases.
 
15:30 Bruno Cessac (INRIA, Sophia Antipolis, France) Ion channels and properties of large neuronal networks: a computational study of retinal waves during development.
 
15:50 Coffee Break
 
16:10 Florian Lesage (IPMC) Pathophysiology of two-pore domain potassium channels.
 
16:30 Guillaume Sandoz (IBV, Nice, France) Two-pore domain potassium channels in migraine.
 
16:50 Marc Borsotto (IPMC) Modulation of Trek1 channels by the peptide spadine: novel therapeutic strategies in pathologies of the nervous system.
 
17:10 Philippe Lory (IGF, Montpellier, France) Calcium channels’ dysfunctions in ataxia and epilepsy.
 
17:40 Thomas Maurin (IPMC) Deregulation of Cav2 calcium channels in a mouse model of Fragile X. 
 
17:55 General discussion
 
18:10 End of the symposium

IPMC

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Symposium on Ion channels and Channelopathies - IPMC

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