The Journée de la Recherche Translationnelle (Translational Research Day) is a full-day mini-symposium dedicated to translational research organized by the Centre de recherche Translationnelle, that supports innovative biomedical research from bench to bedside and back. It gathers each year about 200 scientists and clinicians on a specific topic. This event is organised at Institut Pasteur since 2007. This year the conference is organized in partnership with the Cancer Initiative and Vaccinology and Immunotherapy Initiative of Institut Pasteur.

Journée de la recherche translationnelle

                                     - Cancer & Immunotherapy -

April 2nd, 2021, Institut Pasteur, Paris

• [Keynote] What is the future for immunotherapy? Caroline Robert, France

• A twist in cancer immunotherapy: IL-8 and NETs in solid tumors - Ignacio Melero, Spain

• Exploiting DNA repair defects to stimulate anti-cancer immunity: example of PARP inhibitors - Sophie Postel Vinay, France

• Chromatin role of SUMO in innate immunity - Anne Dejean, France

• Heterogeneity of the Myeloid Compartment and its Stromal Interactions in Triple-negative Breast Cancer - Emanuela Romano, France

• [Short presentation] Multiscale analysis of the initiation of the immune response reveals that collective T cell behaviours govern tumour regression - Gustave Ronteix, France

LUNCH break

• [Keynote] Capturing heterogeneity and the HLA-presented landscape in melanoma -Yardena Samuels, Israel

• Splicing patterns in SF3B1 mutated uveal melanoma generate public immunogenic tumor-specific neo-epitopes - Olivier Lantz, France

• Decoding the mode of action of tumor immunotherapies using intravital imaging - Philippe Bousso, France

• [Keynote] CD19 CAR therapy: the first synthetic immune response - Michel Sadelain, USA

Organizing committee : Ludovic Deriano, James di Santo, Sergio Roman-Roman, Bruno Hoen, Clémentine Schilte, Lydie Texier

Download the program with timing