Netherlands Society on Biomolecular Modelling Fall Meeting

Full programme and list of posters:

https://www.bio2byte.be/static_tools/NSBM2022_programme_and_posters_electronic.pdf

Sessions:

• Structural bioinformatics in the age of AlphaFold2

Keynote speaker: Gert Vriend, Senior Professor Bioinformatics of Macromolecular Structures and director of the CMBI bioinformatics institute at the Nijmegen Centre for Molecular Sciences at the Radboud University Medical Centre.

• Proteomics & Protein Structure

Keynote speaker: Ron Heeren, M4I, Professor and Limburg co-chair of the Maastricht Multimodal Molecular Imaging Institute, Maastricht University

• Large scale AlphaFold2 analyses

Keynote speaker: Christine Orengo, Professor of Bioinformatics at University College London (UCL)

• Probabilistic approaches to protein conformation

Keynote speaker: Max Bonomi, CNRS researcher and group leader of the “Integrative structural biology of dynamic systems” team

Final programme :

9:15 - 9:55 Arrival, coffee, poster setup

9:55 - 10:00 Welcome word

10:00 - 10:45 Session 1: Structural bioinformatics in the age of AlphaFold2 (Gert Vriend)

10:45 - 11:30 Session 2: Proteomics & Protein Structure (Ron Heeren)

11:30 - 12:15 Flash talks from submitted abstracts (3 presentations of 10min + 5min Q&A)

- Ida de Vries: AlphaFill: Enriching the AlphaFold models with co-factors, small molecules and metal ions.

- Marius Wanko: Mechanism of enzyme inhibition by nanobody: from molecular structure to molecular dynamic.

- Hessel Poelman: The cation-π interaction: lost in normalization.

12:15 - 13:00 Lunch break

14:30 - 15:15 Session 4: Probabilistic approaches to protein conformation (Max Bonomi)

13:00 - 13:45 Poster session

13:45 - 14:30 Session 3: Large scale AlphaFold2 analysis (Christine Orengo)

15:15 - 16:00 Flash talks from submitted abstracts (3 presentations of 10min + 5min Q&A)

- Alexander Gress: Features derived from protein 3D structure improve prediction of variant effects in novel proteins.

- Athanasios Baltzis: nf-core/proteinfold: a bioinformatics best-practice pipeline for protein 3D structure prediction.

- Mainak Guha Roy: SNPeffect 5.0: Large-scale structural phenotyping of protein coding variants extracted from next-generation sequencing data using AlphaFold models.

16:00 - 16:10 Closing speech & poster prize

16:10 - end Networking and reception

Key dates:

• Abstract submission deadline for talks: 16th October
• Communication for speakers: 20th October
• Deadline registration: 23th October
• Abstract submission deadline for posters: 16th October

Abstract submission:

• Via Easychair: https://easychair.org/cfp/NSBM2022

Sponsors:

• Elixir Belgium
• FWO Scientific Research Network ‘Novel Knowledge from Public Life Sciences Data’
• Structural Biology Brussels
• Belgian Biophysical Society

Want to be a sponsor?

• Contact us via email on nsbm2022@ibsquare.be

How to arrive from the Netherlands?

• Via Intercity Brussels to Brussel Centraal, then Metro 5 to Pétillon. (This ticket allows to take any IC Brussels any time of the day).
• Via Thalys or Eurostar to Brussels Midi, then Metros 2 or 6 until Kunst-Wet and Metro 5 until Pétillon