The COST Action EnGagE organizes a workshop in Paris entitled « the Principles of Psychiatric Genetic Testing & Counselling » on April 11-12th.

The last decade has witnessed major advances in psychiatric genetics. Research have received wide media coverage and awareness among patients and their family members leading to an increased demand for high-quality information on psychiatric genetics. However, development of the psychiatric testing and counseling in Europe is heterogeneous and a framework to facilitate the implementation of both disciplines into routine clinical care is lacking. The COST Action EnGagE aimed to strengthen pan-European research into the newly emerging disciplines of Psychiatric Genetic Counselling and Psychiatric Genetic Testing.

This first workshop of the Action aims to bring together child and adult psychiatrists, psychologists, clinical geneticists, genetic counselors, and students from all over Europe to develop a shared culture. The two days will be split in four sections :

Thursday morning: “Presentation of the French initiatives in psychiatric genetics and introduction to psychiatric disorders”
Thursday afternoon: “Introduction to genetic counseling”
Friday morning: “Introduction to genetic testing”
Friday afternoon: “Patient perspectives”

Lunch and coffee breaks will be offered.

A call for poster presentation is opened. If interested, please send an email to boris.chaumette@inserm.fr

Organisation committee: Dr. Boris Chaumette, Pr. David Cohen, Dr. Franziska Degenhardt, Pr. Marie-Odile Krebs, Dr. Claudine Laurent-Levinson

Program

Thursday, April 11th

9.00-9.30 : Welcome introduction (T. Galli, MO. Krebs, F. Degenhardt)

9.30-10.00 : Presentation of the French initiatives: Reference Center for Rare Psychiatric Diseases, DefiScience network and France Genomic 2025 Initiative (D. Cohen)

10.00-10.30 : The genetic architecture of autism from risk to resilience (T. Bourgeron)

Coffee Break and Networking

Session Psychiatric Disorders

11.00-11.30 : Introduction to Psychiatric disorders (B. Chaumette)

11.30-12.00 : Clinical neurogenetics of psychiatric disorders (A. Poisson)

12.00-12.30 : Clinical red flags for organicity in schizophrenia (O. Bonnot)

12.30-13.00 : Medical and genetic risk factors in early-onset psychosis (C. Laurent-Levinson)

Lunch, Poster session and Networking

Session Genetic Counselling

14.00-14.30 : Psychiatric information and genetic counselling - How are we doing? (A. Cuthbert)

14.30-15.30 : Clinical and personal utility of genetic diagnoses in individuals with neuropsychiatric disorders (B. Finucane)

15.30-16.00 : Discussion and questions

Coffee break and Networking

16.30-17.30 : Artificial intelligence for facial images: is there a characteristic gestalt in schizophrenia? (P. Krawitz)

17.30-18.30 : Recent and future developments in medical genetics (S. Lyonnet

19.00-22.00 : Dinner (by invitation only)

Friday, April 12th

Session Genetic Testing

9.00-9.45 : Short introduction to genetic testing with focus on chromosomal microarray (K. Tammimies)

9.45-10.15 : Medical consequences of pathogenic CNVs among carriers in the UK biobank (G. Kirov)

10.15-10.30 : Round table discussion

Coffee break and Networking

11.00-12.00 : 22q11.2 deletion syndrome and the clinical application of genetic testing and genetic counselling for major psychiatric illness (A. Bassett)

12.00-13.00 : Modelling the effect-size of rare variants, genome-wide, on cognitive and behavioural traits (S. Jacquemont)

Lunch, Poster session and Networking

Session Patient perspectives

14.00-14.30 : New therapeutic advances in Prader-Willi syndrome (M. Tauber)

14.30-15.15 : Unique: Supporting & informing families and professionals challenged by rare chromosome & genome disorders (B. Searle)

15.15-15.30 : Discussion and closing remarks

After 15.30 : Tour of the Institute of Psychiatry and Neuroscience of Paris and the Sainte-Anne hospital

L'Action COST EnGagE organise à Paris un atelier intitulé «Les principes du dépistage génétique et du conseil psychiatriques» les 11 et 12 avril.

La dernière décennie a été témoin d'avancées majeures en génétique psychiatrique. Les recherches ont bénéficié d'une large couverture médiatique et d'une prise de conscience parmi les patients et les membres de leur famille, ce qui a entraîné une demande accrue d'informations de qualité sur la génétique psychiatrique. Cependant, le développement du conseil et des tests psychiatriques en Europe est hétérogène et un cadre facilitant la mise en œuvre des deux disciplines dans les soins cliniques de routine fait défaut. L'action EnGagE vise à renforcer la recherche paneuropéenne sur les disciplines émergentes du conseil génétique en psychiatrie et des tests génétiques psychiatriques. Ce premier atelier de l'action vise à réunir des psychiatres pour enfants et adultes, des psychologues, des généticiens cliniques, des conseillers en génétique et des étudiants de toute l'Europe pour développer une culture commune.

Les deux jours seront divisés en quatre sections:

Jeudi matin: «Présentation des initiatives françaises en génétique psychiatrique et introduction aux troubles psychiatriques»
Jeudi après-midi: "Introduction au conseil génétique"
Vendredi matin: "Introduction aux tests génétiques"
Vendredi après-midi: “Perspectives du patient”

Le déjeuner et les pauses café seront offerts.

Un appel à la présentation par affiches est ouvert. Si vous êtes intéressé, veuillez envoyer un email à boris.chaumette@inserm.fr

Comité d'organisation: Dr. Boris Chaumette, Pr. David Cohen, Dr Franziska Degenhardt, Pr. Marie-Odile Krebs, Dre Claudine Laurent-Levinson

EnGagE : Enhancing Psychiatric Genetic Counselling, Testing, and Training in Europe